Advanced biomedical engineering by Gaetano D Gargiulo; Alistair McEwan

By Gaetano D Gargiulo; Alistair McEwan

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High-throughput platforms, such as microarrays, enable the scientists to simultaneously interrogate the expression abundance of tens of thousands of genes in the living cell. A microarray experiment is typically performed by hybridizing target cRNA samples labeled with fluorescent dyes on a glass slide spotted with oligonucleotides. After hybridization, the glass slide is washed and scanned to detect the gene expression levels. Some of the popular microarray platforms include Affymetrix GeneChip, Agilent Microarray, Illumina BeadArray and housemade twocolor arrays.

121, 2858–2866. O’Rourke, MF & Mancia, G. (1999) Arterial stiffness. J Hypertens. 1999;17:1–4. ; Pauca, A. & Jiang, X-J. (2001) Pulse wave analysis. Br J Clin Pharmacol. 2001; 51: 507–522. ; Lloyd-Jones, DM. & Baker, DW. (2009) Electronic health recordbased cardiac risk assessment and identification of unmet preventive needs. Med Care 47:418–424, 2009 Postel-Vinay, MC. (1996) Growth hormone- and prolactin-binding proteins: soluble forms of receptors. ; Liebold, A. & Hobbhahn, J. (1999). Continuous cardiac output measurement: pulse contour analysis vs thermodilution technique in cardiac surgical patients.

2. 833E-019). A closer relationship could be found between adjusted Stiffness Index and age. 279E-040) In order to test the sensitivity of primary factor SI, we compare it with the collected data from different groups. 751). On the other hand, it has positive correlation with age for both groups. All people in patients group came from the Department of Cardiology at Shandong Provincial Hospital and most of them have atherosclerosis which is the main reason for arterial stiffness. This result shows that the SI is a significant factor in pulse wave analysis to detect the degree of arterial stiffness.

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